Cancer Carcinogenesis

Cancer Carcinogenesis Photo Carcinogenesis or oncogenesis or tumorigenesis is the formation of a cancer, whereby normal cells are transformed into cancer cells. The process is characterized by changes at the cellular, genetic, and epigenetic levels and abnormal cell division, in some cancers forming a malignant mass.Some of the theories of carcinogenesis is (i) Gene mutation theory (ii) Aneuploidy theory (iii) Epigenetic theory. Biological factors that cause cancer is (i) Age and Hormonal status (ii) Family history (iii) Genetic predisposition. External factors that causes cancer is (i) Tobacco (ii) Alcohol (iii) Radiations and (iv) Viruses
  • Radiation-induced cancer
  • Carcinogens-Ultimate carcinogens, Procarcinogens,Co-carcinogen
  • Carcinogens in Tobacco Products
  • Overview of genotoxic carcinogens and non-genotoxic carcinogens
  • Mechanism of oncogene activation
  • Mechanism of Proto-oncogene activation
  • Functions of Tumor suppressor genes
  • Significance of multiple mutations in cancer
  • Transformation of Oncogene viruses

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