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Theme
Integrating and Innovating the Ideas of Cancer Therapeutics
- Cancer Therapeutics 2017

About

                                           

                             

Allied Academies was founded by Jim and JoAnn Carland and the headquarters is located in North Carolina in United States of America. It conducts several academic conferences each year in different locations with internet participation possibilities for those who are physically unable to attend the conferences. Conference registrants are eligible for the Accelerated Journal Review. To provide you with maximum outlets for your research, Allied Business Academies holds joint meetings of all its member academies. In 1994 they launched the Journal of the International Academy of Case Studies, which has become a leader in publishing classroom teaching cases in business.  

Cancer is a group of diseases that is caused due to abnormal cell growth and their potential to invade or spread to other parts of the body. Benign tumors do not spread to other parts of the body. There are more than 100 types of cancer including breast cancer, skin cancer, lung cancer, colon cancer, prostate cancer, and lymphoma. Symptoms vary depending on the types of cancer . Cancer treatment may include chemotherapy, radiation, and/or surgery.

Cancer Therapeutics 2017 is the great platform for everybody to put forth their ideas of Cancer research. The main theme of the conference is “Integrating and Innovating the Ideas of Cancer Therapies”. So, Lets all join together and fight against Cancer. 

Why Toronto?

Toronto local is the most populous city in Canada, the provincial capital of Ontario, and the center of the Greater Toronto Area, the most populous metropolitan area in Canada. Growing in population, the 2011 census recorded a population of 2, 615,060.As of 2015, the population is now estimated at 2, 826, 498, making Toronto the fourth-largest city in North America based on the population within its city limits. Toronto trails only Mexico City, New York City, and Los Angeles by this measure, while it is the fifth-largest (behind also Chicago) if ranked by the size of its metropolitan area .An established global city, Toronto is an international center of business, finance, arts, and culture, and widely recognized as one of the most multicultural and cosmopolitan cities in the world. Toronto is home to 20 public hospitals, including: the Hospital for Sick Children, Mount Sinai Hospital, St. Michael's Hospital, North York General Hospital, Toronto General Hospital, Toronto Western Hospital, St. Joseph's Health Centre, Rouge Valley Health System, The Scarborough Hospital, Sunnybrook Health Sciences Centre, Centre for Addiction and Mental Health (CAMH), and Princess Margaret Cancer Centre, as well as the University of Toronto Faculty of Medicine. Most popular institute for Cancer Research in Canada is “The Ontario Institute for Cancer Research (OICR) and Princess Margaret Cancer Centre. The Ontario Institute for Cancer Research (OICR) is a not-for-profit organization based in Toronto, Ontario, Canada that focuses on the prevention, early detection, diagnosis and treatment of cancer. OICR intends to make Ontario more effective in knowledge transfer and commercialization while maximizing the health and economic benefits of research findings for the people of Ontario. OICR was launched in 2005 by the Government of Ontario, which provides funding through the Ministry of Research, Innovation and Science. The Institute employs more than 350 people at its research hub at the MaRS Centre in downtown Toronto and funds more than 1,700 scientific staff at hospital-based research institutes and universities around the province. 

Welcome Message

Allied Academies welcomes you all with a great pleasure and honor to extend a warm invitation to attend the “International Conference on Cancer Biology and Therapeutics 2017” which is to be held on Oct 23-24, 2017 in Toronto, Ontario, Canada.

The Main theme of the conference is “Integrating and Innovating the Ideas of Cancer Therapeutics".

Cancer Therapeutics 2017 will be a great platform for research scientists and young researchers to share their current findings in the field of applied sciences.

Market Analysis


                                                                          


INTRODUCTION

Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Not all tumors are cancerous, benign tumors do not spread to other parts of the body. Possible signs and symptoms include lump, abnormal bleeding, prolonged cough, unexplained weight loss and a change in bowel movements. While these symptoms may indicate cancer, they may have other cauese also. Over 100 cancers affect humans. 

STUDY OBJECTIVES

BCC’s goal in conducting this study is to provide an overview of the current and potential aspects of the global market for cancer therapies. The report determines the market size, market leaders, and factors affecting the market for cancer therapies with the inclusion of the market by disease sector. The overview of types of diseases and different therapies in cancer are also examined along with sale figures over the 5-year period from 2008 to 2013. Companies manufacturing/selling the drugs to treat cancer are profiled, and the factors affecting markets for these products and how those markets are likely to change are analyzed. Revenues have been broken down by the type of therapies and by different regions.

Our key objective is to present a comprehensive analysis of the current and future market and to analyze the future direction of cancer therapies with an emphasis on newer products. The global market for lung cancer grew to $21.9 billion in 2014 from $20.3 billion in 2013. The market is expected to grow at a five-year compound annual growth rate (CAGR) of 7.8% from 2014 to 2019, totaling $31.8 billion in 2019. The hallmark of cancer is uncontrolled growth and the spread of abnormal cells. The disease leads to more than 6 million deaths worldwide each year. The American Cancer Society (ACS) estimates that more than 12 million new cases of cancer are diagnosed worldwide each year.  Tremendous progress has been seen in the early diagnoses and treatment methods for cancer during the past few years. Sadly, most of the current methods still in use are conventional therapies such as surgery, radiation, and chemotherapy, all with intense and serious side effects.

REPORT SCOPE

The report will analyze the cancer market as per diagnostics and therapeutics, and will also focus on the regulations and government supported programs impacting this market. Regionally, the focus of study will be the markets of North America, Europe, Asia-Pacific and Rest of the World (ROW).This report includes various lung cancer diagnostics tests like histology/cytology, immunoassays, flow cytometry, rapid tests, molecular assays, tissue arrays, circulating tumor cells, pharmacodiagnostics, and molecular biomarkers, etc. Lung cancer therapeutics includes chemotherapy, radiotherapy and surgery.

The global market for lung cancer grew to $21.9 billion in 2014 from $20.3 billion in 2013. The market is expected to grow at a five-year compound annual growth rate (CAGR) of 7.8% from 2014 to 2019, totaling $31.8 billion in 2019

Sessions/Tracks


Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Benign tumors do not spread to other parts of the body. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss and a change in bowel movements

  • Past present and future of Molecular and Cellular Progress in Oncology
  • Development in Cancer Genomics and Systems Biology
  • The general Pathophysiology of Cancer
  • Fundamentals of Tumor Metabolism
  • An overview of Pharmacoeconomics 


Organ Specific Cancers are cancers named baseing on thel ocation of cancer in the body organ. Its incidence is showing an increasing trend in various parts of the earth and has been a significant public health problem despite advances in the understanding of the molecular and cellular events that underlie.


  •  Anal cancer, Bladder cancer, Bone cancer
  •  Bowel cancer, Brain cancer, Breast cancer
  •  Cervical cancer, Head and neck cancer, Kidney cancer
  •  Leukemia, Liver cancer, Lung cancer
  •  Lymphoma, Myeloma, Ovarian cancer
  •  Pancreatic cancer, Prostate cancer, Skin cancer
  •  Stomach cancer, Thyroid cancer


Carcinogenesis or oncogenesis or tumorigenesis is the formation of a cancer, whereby normal cells are transformed into cancer cells. Biological factors that cause cancer is (i) Age and Hormonal status (ii) Family history (iii) Genetic predisposition. External factors that causes cancer is  (i) Tobacco (ii) Alcohol (iii) Radiations and (iv) Viruses.


  • Radiation-induced cancer
  • Carcinogens, ultimate carcinogens, Pro-carcinogens, Co-carcinogen 
  • Carcinogens in Tobacco Products
  • Overview of genotoxic carcinogens and non-genotoxic   carcinogens
  • Mechanism of oncogene activation        
  • Mechanism of Proto-oncogene activation
  • Functions of Tumor suppressor genes
  • Significance of multiple mutations in cancer
  • Transformation of Oncogene viruses

Cancer can be cured if it is diagnoized early. There are several methods of diagnosing cancer. With advances in technologies that understand cancers better, there is a rise of number of diagnostic tools that can help detect cancers. 

  • Colonoscopy, sigmoidoscopy, and high-sensitivity fecal occult   blood tests (FOBTs)
  • Low-dose helical computed tomography
  • Mammography: Benefits and Risks
  • Pap test and human papillomavirus (HPV) testing
  • Alpha-fetoprotein blood test for Liver cancer screening
  • Breast Magnetic Resonance Imaging (MRI)
  • Role of Cancer Antigen-125 in diagnosis of cancer
  • Screening of Prostatic carcinoma using Prostate-specific antigen test (PSA)
  • Transvaginal ultrasound-Purpose and Procedure 
  • Virtual colonoscopy for colorectal cancer screening
  • Nanoshell-Enabled Photonics-Based Imaging of Cancer
  • Positron Emission Tomography and Computed Tomography (PET-CT)  Scans                    


Cancer can be treated according to the type and stage of cancer. Some of the main types of treating cancer is by Surgery. In surgery the infected part would be completely removed. Radiation therapy is a cancer treatment in which high dose of radiation is given to the tumor cell to shrink the tumors. Chemotherapy is a treatment where drugs are used to kill the tumors. Precision medicine is an approach to patient care for the doctor to give the treatment according to their genes. It is also called as personalized medicine.


  • Role of Conventional surgeries in cancer treatment
  • A Guide to Radiation Therapy 
  • Chemotherapy improves survival and quality of life in advanced pancreatic and biliary cancer
  • Potential benefits of precision medicine


Gene therapy is a type of treatment which uses genes to treat illnesses. Researchers hope that some types of gene therapy will be able to treat cancer. The idea of these treatments has come because the genetic character changes from person to person. Strategies of Gene therapy is to enhance the immunogenicity of the tumors, to enhance immune cells to increase anti-tumor activity and Killing tumor cells by inserting toxin genes under the control of a tumor-specific promoter


  • Boosting the immune response
  • Gene therapies to make cancer treatments work better
  • Pro drug gene therapy
  • Blocking processes that protect cancer cells Using altered viruses
  • Mechanism of Somatic cell gene therapy (SCGT)
  • Mechanism of Germline gene therapy (GGT)

 

Biomarkers are characteristics that are objectively marked biomarkers are characteristics that are objectively measured and evaluated as indicators of normal biological processes, pathogenic processes, and pharmacological responses to a therapeutic intervention


  • Role of biomarkers in cancer research and medicine
  • Developing drug targets in biomarkers for cancer research
  • Surrogate endpoints in cancer clinical trails
  • Types of Molecular cancer biomarker
  • Clinical biomarkers in cancer drug discovery and development



Stem cell transplants are procedures that restore blood-forming stem cells in people who have destroyed their cells by radiation or very high dose of chemotherapy that are used to treat certain cancers. Stem cells are very early blood cells in the bone marrow that develop into red blood cells, white blood cells and platelets. We need stem cells in order to survive. The cord blood cells are collected from the umbilical cord and placenta of the new born baby. 


  • Cancer stem cells in solid tumors
  • Stem Cell Therapy for Cancer treatment
  • Hematopoietic stem cells: potential new applications for translational medicine
  • Human umbilical cord blood as an emerging stem cell therapy for cancer

There are some lists of drugs which can be used for treating cancer. The quantity of the drug differs according to the sensitivity of the tumor cells. Clinical trials are used to test the new cancer treatments, which involves a series of phases. During Early phase researchers figure out the side effects and best dose of the new treatment. Its rate on slowering the growth of the tumor cell is also observed by the researchers. Recent days, Genomics and nanotechnology is the developing field for anti-cancer drug development. Most of the anti-cancer drugs are taken orally.


  • Quantitation of differential sensitivity of human-tumor stem cells to anticancer drugs
  • Different Phases of cancer Clinical Trails
  • Impact factor of Toxicology and Drug Metabolism
  • Future of Molecular medicine in cancer treatment
  • Treatment of Cancer with Oral Drugs
  • Functional Genomics in Drug Discovery
  • Novel Drug Delivery System
  • Nanotechnology in Cancer Drugs


Certain cancers like cervical, Anal, Throat are caused due to Human Papilloma Virus (HPV). People with the chronic infections of Hepatitis B Virus (HBV) have a great risk of liver cancer. Vaccines that help protect against infections with these viruses might also help prevent some of these cancers. Cancer treatment vaccines are different from the vaccines that work against viruses. These vaccines try to get the immune system to mount an attack against cancer cells in the body. Instead of preventing disease, they are meant to get the immune system to attack a disease that already exists. Sipuleucel-T is the only vaccine for cancer approved by USA


  • Therapeutic vaccines for cancer: an overview of clinical trials
  • Whole Cell Vaccines-Past Present and Future Strategies
  • Immune Response to vaccine antigens
  • The Emerging Role of DNA Vaccines
  • Oncolytic viruses- A new class of immunotherapy drugs
  • Cancer Vaccine Research Trials future opportunities


Targeted therapy is the foundation of precision medicine. It is a type of cancer treatment that targets the changes in cancer cells that help them grow, divide, and spread. As researchers learn more about the cell changes that drive cancer, they are better able to design promising therapies that target these changes or block their effects.Some targeted therapies block (inhibit) enzymes that are signals for cancer cells to grow. These drugs are called enzyme inhibitors. Blocking these cell signals can keep the cancer from getting bigger and spreading. So even if the tumor is not getting smaller, its out-ofcontrol growth has been interrupted.


  • EGFR Mutations in Lung Cancer
  • Antiangiogenic Therapy
  • Resistance to STI-571 Cancer Therapy Caused by BCR-ABL Gene mutation
  • Hormone replacement therapies
  • Signal Transduction Inhibitors as Promising Anti-cancer Agents.
  • Gene expression modulators
  • Cancer cell-specific inducer of apoptosis
  • Oncogene - Glycolysis inhibition for anticancer treatment 
  • Mechanism of Angiogenesis inhibitors in cancer therapy
  • The science of Molecular Epidemiology
  • Functions of Toxin-delivery molecules in cancer
  • Role of BRCA1 and BRCA2 in cancer therapeutics

Immunotherapy is a type of cancer treatment that helps your immune system fight cancer. The immune system helps your body fight infections and other diseases. It is made up of white blood cells and organs and tissues of the lymph system.  


  • Monoclonal Antibodies, Hybridoma development
  • Roles of cytokines in health and disease
  • Tumor-Associated Antigens for Specific Immunotherapy
  • Functions of Cell Surface Receptors
  • Malignant Melanoma prognosis
  • Role of Lymphocytes in immune therapy and cancer
  • Re-programming the immune system 

Nanotechnology an extremely wide and versatile field, can affect many of its composing disciplines in amazingly innovative and unpredictable ways. In fact, nanotechnology and the ideas and methods that it encompasses can be applied to almost any problem that leading researchers face today. Even the most seemingly impossible problems like HIV and cancer become only obstacles in the path to solutions. Nanotechnology can be used in several clinical applications. Nanotechnology is used in the diagnosing, detecting and treating of the tumor cells.


  • Function of Tumor Microenvironment in Cancer Progression
  • Function of Chemo Drugs in cancer
  • Stealth Nanoparticles and Tumor Penetrating Peptides
  • Vector-host interactions governing epidemiology
  • New Nanomaterials in treatment of cancer
  • Imaging and drug delivery using Theranostics nanoparticles
  • Early Diagnosis and Imaging of cancer using nanoparticles
  • Advances in Nanotechnology

Biological therapies use the living organisms and the substance released from the biological organs to treat disease. Some biological therapies of cancer use vaccines or bacteria to stimulate the body's immune system to act against cancer cells. These types of biological therapy, which are sometimes referred collectively as "Immunotherapy" or "Biological response modifier therapy", do not target cancer cells directly. Other biological therapies, such as antibodies or segments of genetic material (RNA or DNA), do not target cancer cells directly


  • Bacillus Calmette-Guérin therapy in cancer treatment
  • Oncolytic viruses & their specific targeting to tumor cells
  • Role of Vaccine therapy in cancer
  • Adoptive T-cell immunotherapy for cancer
  • Oncolytic viruses in cancer therapy
  • DNA oligonucleotide therapy for cancer
  • RNA oligonucleotide therapy for cancer
  • Inhibition of proliferation of cancer cells using Penicillin
  • Mechanism of Cephalosporins in Cancer cells Pharmacokinetics of Vancomycin in cancer patients

Hematology-oncology is diagnosis, treatment and prevention of blood related diseases like Anemia, Leukemia, Sickle cell diseases and Thalassemia. It also deals with the study of blood tissue related diseases also. Hematology is the study of all blood related problems; it treats bleeding disorder such as Hemophilia, Idiopathic thrombocytopenic purpura. It is used in the science of blood transfusion.


  • Classification of Blood Malignancies 
  • Myeloma-Symptoms and prognosis
  • Lymphoma- Hodgkin Lymphoma and Non-Hodgkin Lymphoma
  • Leukemia-Symptoms and treatments
  • Thalassemia-Causes, symptoms and Diagnosis
  • Sickle Cell Disease-Prognosis and complications
  • Haemophilia-Complications , management and  treatment
  • Treatment strategies for Solid Tumors

This report studies the global cancer diagnostics market for the forecast period of 2015 to 2020. This market is expected to reach $13.1 Billion by 2020 from $7.1 Billion in 2015, and is poised to grow at a CAGR of 12.9% during the forecast period. The global cancer diagnostic market is segmented into technology, application and region. Based on technology, the cancer diagnostics market is categorized into platform-based and instrument-based.


  • Enzyme-Linked ImmunoSorbent Assay (ELISA)
  • Enzyme-Linked Fluorescence Assay (ELFA)
  • Polymerase chain reaction (PCR)
  • Next generation sequencing (NGS) 
  • Overview of Immunohistochemistry
  • DNA Microarray methodology for detection and identification of cancer
  • Medical uses of Magnetic Resonance Imaging
  • Computer Tomography and Cancer 
  • Purpose, Procedure and Risk of Positron Emitted Tomography 
  • Ultrasound for Cancer diagnosis
  • Types of Biopsy procedures in cancer

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At the beginning of the last century, one out of 20 was affected with cancer, in 1940's it got increased to one out 16, later in 1970's one person out of ten was affected with cancer. Now it was one out of three is affected with cancer. Large percentage of cancer treatment is directly involved in chemotherapy drugs. Cancer patients get 6-12 months of chemotherapy for their initial treatment.  Pharmaceutical industry has an powerful hold on the entire medical system in U.S, and they are not about to let any alternative medicines for cancer. 

  • Medical Research and the Cancer Factory
  • Government Oversight and the Cancer Machine
  • Charitable Fundraising in Pharma industry for cancer research 
  • An overview of Chemotherapy Drug Industry


The risk of cancer can be reduced possibly through diet and other lifestyle change. Tobacco is directly associated with cancer, so avoiding tobacco can reduce the risk of lung cancer. Decreasing the level of alcohol can decrease the risk of neck throat and esophageal cancer. Physical activity to reduce the risk of cancer. Covering exposed skin by using, sunscreen lotions to reduce the risk of skin cancer or Melanoma. Cancer can be managed by many treatments like chemotherapy, radiation therapy, hormonal therapy, target therapy and palliative care.


Paediatric oncology is the malignant conditions in children. In the United States an arbitrary adopted the standard of the ages used are 0-14, definition of childhood cancer sometimes also includes the age group 0f 14-19. Paediatric oncology is defined as the study of diagnoizing and treatment of cancer in children’s. Worldwide it is estimated that, childhood cancer has an incidence of 175,000,000 per year, and the mortality rate is 96,000 per year.


  • Retinoblastoma in children
  • Steosarcoma Cancer: Diagnosis, Treatment, Research & Support
  • Genetically engineered Fusion oncoproteins in treatment of cancer

Cancer treatment sometimes damages a body part function or organ. Reconstructive surgery helps to repair that damage. Reconstructive surgery is mostly needed after some type of cancer surgery or remove cancer. Reconstructive surgery can be done after a mastectomy. A mastectomy is a surgical removal of organ (breast). Many reconstructive surgeries use microvascular technique. Microvascular technique called "fee flap surgery". A damaged part of a body is replaced by artificial implantation. Scar revisions surgery is used to minimize the appearance of scar after surgery. 

  • Plastic & Reconstructive Surgery for women
  • Local flap surgery for melanoma
  • Artificial implants of organs 
  • Scar Revision - Improve the Appearance of Scars
  • Process of Skin, tendon, and bone grafting 

Over the last two centuries, cancer treatment has evolved from the most primitive surgical treatments to highly advanced targeted therapies, which work by influencing the processes that control growth, division, and spread of cancer cells.  Cancer research is continuing to advance on many fronts, from immunotherapies to robot surgeries to gene therapies.  Tumors disable the immune system's killer T cells, which can find and destroy certain cancer cells. Immunotherapy drugs work by preventing tumors from using this devious tactic. But if no T cells are swarming the tumor in the first place, the drugs don't help


  • Precision Medicine: Interpreting the Story of Genes
  • Checkpoint Inhibitors: Triggering Immune Defense        
  • Chimeric Antigen Receptors Modified T-Cells for Cancer Therapy
  • Epigenetic Therapy: Setting Cancer Cells Straight
  • Research into Metastasis: Unmasking the Latent Enemy
  • Approaches for Translational Oncology 

Drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Later, synthetic small molecules, natural products are extracts were screened in intact cells or whole organism to identify substances that have a desirable therapeutic effect in a process known as classical pharmacology. Since sequencing of human genome which allowed rapid cloning and synthesis of large quantities of purified proteins, it has become common practice to use high throughput screening of large compounds libraries against isolated biological targets which are hypothesized to be disease modifying in process called reverse pharmacology.


  • Preclinical research: drug discovery and initial testing
  • Drug developers and sponsors
  • Clinical research on drug discovery
  • Clinical review and FDA approval
  • In-vitro metabolism in drug development
  • Plasma protein binding data for animals and humans 
  • Systemic exposure data in the species used for repeated-dose toxicity studies 

The Normal treatment modalities are associated with severe side effects and high toxicity which in turn lead to low quality of life. This review encompasses novel strategies for more effective chemotherapeutic delivery aiming to generate better prognosis.


  • Molecular cancer therapeutics
  • Clinical and potential applications of metabolomics in oncology
  • Metabolomics in novel biomarker discovery
  • Revisiting tumor metabolism
  • Telomerase: A target for cancer therapeutics
  • Analytical and bio-analytical techniques in metabolomics
  • Transcriptomics
  • Toxicology and drug metabolism

To Collaborate Scientific Professionals around the World

Conference Date October 23-24, 2017
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